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Stabilized Stat3 Decoy Oligonucleotides And Uses Therefor
Stabilized Stat3 Decoy Oligonucleotides And Uses Therefor
The present invention is based, at least in part, on novel, unimolecular STAT3 oligonucleotide decoys exhibiting increased in vivo stability as compared to previously known decoys which are effective in inhibiting STAT3 when administered systemically. The invention is also based on pharmaceutical compositions comprising these unimolecular decoys, and methods for using these decoys in the treatment of cancer.
Original Text (This is the original text for your reference.)
The present invention is based, at least in part, on novel, unimolecular STAT3 oligonucleotide decoys exhibiting increased in vivo stability as compared to previously known decoys which are effective in inhibiting STAT3 when administered systemically. The invention is also based on pharmaceutical compositions comprising these unimolecular decoys, and methods for using these decoys in the treatment of cancer.
Inventor: Jennifer R. Grandis,Daniel Johnson,Danith Ly
Application number: 13491343
Publication number: 20120288536
Filing date: 2012-06-06
Publication date: 2012-11-14
Type of Patent: A1
Source: IKCEST
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