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With PARP inhibitor for treating Small Cell Lung Cancer

Abstract

This document describes the methods with poly- (ADP- ribose) polymerase (PARP) inhibitor or the Small Cell Lung Cancer subject of its pharmaceutically acceptable salt treatment expression Schlafen-11 (SLFN11).Specifically, the method includes detecting SLFN 11 in the tumor cells specimens from the subject, and a effective amount of PARP inhibitor, the toluene fulfonate of such as talazoparib or talazoparib are applied to the subject.

Original Text (This is the original text for your reference.)

This document describes the methods with poly- (ADP- ribose) polymerase (PARP) inhibitor or the Small Cell Lung Cancer subject of its pharmaceutically acceptable salt treatment expression Schlafen-11 (SLFN11).Specifically, the method includes detecting SLFN 11 in the tumor cells specimens from the subject, and a effective amount of PARP inhibitor, the toluene fulfonate of such as talazoparib or talazoparib are applied to the subject.

Inventor: EVELYN WANG;EVELYN WANG;KAREN YU;KAREN YU;LEONARD E. POST;LEONARD E POST;YING FENG;YING FENG;YUANBIN RU;YUANBIN RU;YUQIAO SHEN;YUQIAO SHEN

Application number: BR112018008503

Publication number: BR112018008503A2

Filing date: 2016-10-26

Publication date: 2020-05-26

Type of Patent: A2

Source: IKCEST

Disclaimer: The translated content is provided by third-party translation service providers, and IKCEST shall not assume any responsibility for the accuracy and legality of the content.
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