This document describes the methods with poly- (ADP- ribose) polymerase (PARP) inhibitor or the Small Cell Lung Cancer subject of its pharmaceutically acceptable salt treatment expression Schlafen-11 (SLFN11).Specifically, the method includes detecting SLFN 11 in the tumor cells specimens from the subject, and a effective amount of PARP inhibitor, the toluene fulfonate of such as talazoparib or talazoparib are applied to the subject.
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This document describes the methods with poly- (ADP- ribose) polymerase (PARP) inhibitor or the Small Cell Lung Cancer subject of its pharmaceutically acceptable salt treatment expression Schlafen-11 (SLFN11).Specifically, the method includes detecting SLFN 11 in the tumor cells specimens from the subject, and a effective amount of PARP inhibitor, the toluene fulfonate of such as talazoparib or talazoparib are applied to the subject.
Inventor: EVELYN WANG;EVELYN WANG;KAREN YU;KAREN YU;LEONARD E. POST;LEONARD E POST;YING FENG;YING FENG;YUANBIN RU;YUANBIN RU;YUQIAO SHEN;YUQIAO SHEN
Application number: BR112018008503
Publication number: BR112018008503A2
Filing date: 2016-10-26
Publication date: 2020-05-26
Type of Patent: A2
Source: IKCEST
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