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Eksperimental'naia i klinicheskaia farmakologiia | Vol.67, Issue.6 | | Pages 3-7

Eksperimental'naia i klinicheskaia farmakologiia

[New directions in GABAergic pharmacology of anxiety and depression].

A V, Kaluev D D, Nutt  
Abstract

New prospects in the use of drugs affecting central GABAergic system for the treatment of anxiety and depressive states are critically assessed. Both clinical (human) and experimental (animal) data on the mutual influence of various GABA-receptor modulators as well as the interaction of GABAergic system with neurohumoral mechanisms of stress are considered. Based on this analysis, new strategies in the GABAergic pharmacotherapy of anxiety and depression spectrum disorders are outlined.

Original Text (This is the original text for your reference.)

[New directions in GABAergic pharmacology of anxiety and depression].

New prospects in the use of drugs affecting central GABAergic system for the treatment of anxiety and depressive states are critically assessed. Both clinical (human) and experimental (animal) data on the mutual influence of various GABA-receptor modulators as well as the interaction of GABAergic system with neurohumoral mechanisms of stress are considered. Based on this analysis, new strategies in the GABAergic pharmacotherapy of anxiety and depression spectrum disorders are outlined.

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A V, Kaluev D D, Nutt,.[New directions in GABAergic pharmacology of anxiety and depression].. 67 (6),3-7.

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