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Polish journal of pharmacology | Vol.45, Issue.2 | | Pages 197-200

The effect of calcium channel blockade during electroconvulsive treatment on cerebral cortical adrenoceptor subpopulations in the rat.

L, Antkiewicz-Michaluk J, Michaluk I, Romańska J, Vetulani

Abstract

Chronic administration of nifedipine (5 mg/kg/day for 10 days) induced some biochemical effects consistent with those of antidepressants: a significant depression in cortical alpha 2-adrenoceptor density and reduction of beta-adrenoceptor affinity; nifedipine co-administration with electroconvulsive treatment potentiated the beta-downregulatory effect of the latter.

Original Text (This is the original text for your reference.)

The effect of calcium channel blockade during electroconvulsive treatment on cerebral cortical adrenoceptor subpopulations in the rat.

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Keywords

betaadrenoceptor affinity nifedipine coadministration cortical alpha 2adrenoceptor density

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L, Antkiewicz-Michaluk J, Michaluk I, Romańska J, Vetulani,.The effect of calcium channel blockade during electroconvulsive treatment on cerebral cortical adrenoceptor subpopulations in the rat.. 45 (2),197-200.

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