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Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid | Vol.19, Issue.1-2 | | Pages 1-13

Application of 2D 1H NMR spectroscopy to the study of the brain, spinal cord, and sciatic nerve.

J C, Beloeil B, Gillet O, Fedeli G, Berenger V, Lombardi F, Marzullo A, Scozzafava

Abstract

Homonuclear 1H 2D NMR spectroscopy (COSY experiments at 400 and 600 MHz) were used to study the rat brain in vivo and the rabbit spinal cord and sciatic nerve in vitro. The following metabolites were identified: lactate, alanine, threonine, GABA, glutamine/glutamate, N-acetyl aspartate, aspartate, taurine, inositol derivatives, choline derivatives, and glucose. The sciatic nerve spectra showed characteristic COSY graphs of saturated and unsaturated fatty acids, and linoleic and linolenic type structures were identified.

Original Text (This is the original text for your reference.)

Application of 2D 1H NMR spectroscopy to the study of the brain, spinal cord, and sciatic nerve.

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Keywords

nerve 2d nmr spectroscopy fatty cosy graphs

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J C, Beloeil B, Gillet O, Fedeli G, Berenger V, Lombardi F, Marzullo A, Scozzafava,.Application of 2D 1H NMR spectroscopy to the study of the brain, spinal cord, and sciatic nerve.. 19 (1-2),1-13.

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