To determine the cytomorphologic spectrum of nipple discharge in florid gynecomastia.During a 22-year period (July 1979-June 2001), nipple discharge from nine males with breast lesions were examined. Smears from four of these cases with histologically documented gynecomastia were reviewed along with the tissue sections.In the three patients with florid gynecomastia the smears were cellular, with numerous benign ductal cells and papillary fragments along with foam cells and inflammatory cells. Epithelial atypia was mild in two cases and moderate in one. One of the three cases had an associated breast lump that showed features of florid gynecomastia on fine needle aspiration cytology. The biopsy from this case showed cystic hyperplasia of the breast similar to that in women with an intraductal papilloma. One case of simple gynecomastia on histology showed two fragments of benign ductal cells with occasional apocrine and foam cells.Nipple discharge in florid gynecomastia may pose problems in identification as the cellularity and atypia may lead to a misdiagnosis of carcinoma.

+More

cytomorphologic spectrum nipple discharge needle cellularity benign ductal cells apocrine inflammatory cells epithelial atypia florid gynecomastia breast cystic hyperplasia misdiagnosis of carcinoma papillary identification

Kusum, Kapila Kusum, Verma,.Cytology of nipple discharge in florid gynecomastia.. 47 (1),36-40.

Kusum, Kapila Kusum, Verma,"Cytology of nipple discharge in florid gynecomastia." 47

Kusum, Kapila Kusum, Verma,"Cytology of nipple discharge in florid gynecomastia."