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Ukrainski? biokhimicheski? zhurnal (1978) | Vol.64, Issue.5 | | Pages 31-7

[Effect of brain cytosol proteins of embryonal and adult animals on RNA-polymerase activity of isolated brain nuclei].

A P, Ivanov A A, Kapralov O Ia, Baryk S V, Gubchenko

Abstract

Cytosol and its fractions obtained by the precipitation with ammonium sulphate and ion-exchange chromatography have been studied for their effect on the RNA-polymerase activity of isolated nuclei. We observed the discrepancies in the action of total cytosol of embryonal, newborn or adult animals on the label's incorporation in RNA. It was found that some fractions increased DNA-polymerase activity of isolated nuclei in cattle embryonal cytosol. The same fractions obtained from adult cytosol did not act in such a way. It was found that most fractions obtained from cytosol of adult brain inhibited the RNA-polymerase activity of brain nuclei.

Original Text (This is the original text for your reference.)

[Effect of brain cytosol proteins of embryonal and adult animals on RNA-polymerase activity of isolated brain nuclei].

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Keywords

dnapolymerase rnapolymerase labels incorporation ionexchange chromatography

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A P, Ivanov A A, Kapralov O Ia, Baryk S V, Gubchenko,.[Effect of brain cytosol proteins of embryonal and adult animals on RNA-polymerase activity of isolated brain nuclei].. 64 (5),31-7.

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