Medullary thyroid cancer (MTC) has high level of clinical aggressiveness as well as high recurrence rate par ticularly metastases in regional lymph nodes. Surgery is single curative treatment method thus only initial appropriate operation volume could improve diseasefree and overall survival. In our study the experience of surgical treatment of 125 MTC patients is analyzing. In 25% of cases there were familial MTC (germline RET/MTC mutation verified) disease and in 75% – sporadic tumors. Comparison of tenyears diseasefree sur vival in two groups with various initial surgery extensions revealed that thyroidectomy associated with central neck dissection as a minimal operation volume has significantly improved longterm diseasefree survival as against to lesser initial surgery extension.

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operation volume longterm diseasefree survival surgery extensions central neck dissection tenyears diseasefree sur vival

P O Rumyantsev,A A Ilyin,U V Rumyantseva,.Choice of surgery extension in medullary thyroid cancer. 5 (2),.

P O Rumyantsev,A A Ilyin,U V Rumyantseva,"Choice of surgery extension in medullary thyroid cancer" 5

P O Rumyantsev,A A Ilyin,U V Rumyantseva,"Choice of surgery extension in medullary thyroid cancer"