Electronic structure and inhibition activity relationship study of curcumin analogs has been established for 29 curcumin analogs on Ethoxyresorufin O-Dealkylation (EROD) reaction using atomic net charge descriptor based on AM1 semiempirical calculations. The QSAR (Quantitative Structure and Activities Relationships) equation model was determined by statistical parameter from multiple regression analysis and leave-one-out cross validation method. The best QSAR equation was described: Keywords: curcumin, QSAR, descriptor, atomic net charge, semiempirical methods.

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ethoxyresorufin odealkylation erod reaction keywords curcumin qsar descriptor atomic net charge semiempirical methods inhibition activity relationship leaveoneout cross validation multiple regression analysis qsar equation statistical parameter structure and activities relationships equation am1 semiempirical

Ajidarma Widiatmoko,.QUANTITATIVE RELATIONSHIP OF ELECTRONIC STRUCTURE AND INHIBITION ACTIVITY OF CURCUMIN ANALOGS ON ETHOXYRESORUFIN o-DEALKYLATION (EROD) REACTION. 7 (1),.

Ajidarma Widiatmoko,"QUANTITATIVE RELATIONSHIP OF ELECTRONIC STRUCTURE AND INHIBITION ACTIVITY OF CURCUMIN ANALOGS ON ETHOXYRESORUFIN o-DEALKYLATION (EROD) REACTION" 7

Ajidarma Widiatmoko,"QUANTITATIVE RELATIONSHIP OF ELECTRONIC STRUCTURE AND INHIBITION ACTIVITY OF CURCUMIN ANALOGS ON ETHOXYRESORUFIN o-DEALKYLATION (EROD) REACTION"