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Neurologia i neurochirurgia polska | Vol.33, Issue.3 | | Pages 551-6

Neurologia i neurochirurgia polska

[The effect of astrocytoma cells on secretion of cytokines by autologous lymphocytes].

J, Kowalski Z, Stachura G, Bierzyńska-Macyszyn A, Madej D, Belowski Z S, Herman  
Abstract

Immunotherapy is one of the experimental methods used in the treatment of brain tumours. The development of astrocytomas is accompanied by decreased activity of lymphocytes, namely inhibition of mitogen-induced proliferation and decreased cytokine secretion, which is an adverse event in the course of disease. In the present study, astrocytoma cells obtained from human tumours and cocultured with autologous lymphocytes inhibited cytokine secretion by those lymphocytes.

Original Text (This is the original text for your reference.)

[The effect of astrocytoma cells on secretion of cytokines by autologous lymphocytes].

Immunotherapy is one of the experimental methods used in the treatment of brain tumours. The development of astrocytomas is accompanied by decreased activity of lymphocytes, namely inhibition of mitogen-induced proliferation and decreased cytokine secretion, which is an adverse event in the course of disease. In the present study, astrocytoma cells obtained from human tumours and cocultured with autologous lymphocytes inhibited cytokine secretion by those lymphocytes.

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J, Kowalski Z, Stachura G, Bierzyńska-Macyszyn A, Madej D, Belowski Z S, Herman,.[The effect of astrocytoma cells on secretion of cytokines by autologous lymphocytes].. 33 (3),551-6.

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