Biliary stent blockage by adherence of bacteria and formation of biofilm is a major problem in endoscopic stenting procedures. We have investigated bacterial adherence to hydrophilic polymer (Hydromer)-coated polyurethane stents in stationary and perfusion experiments. Adherence of gram negative and gram positive organisms under stationary conditions was similar between Hydromer-coated and non-coated control polyurethane stents; however, a marked 1 to 3 log reduction in adherence to Hydromer-coated stents occurred when perfusion experiments in phosphate buffer solution or bile were performed. The results suggest that Hydromer-coated polyurethane stents could be useful in preventing complications caused by biliary stent blockage.

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organisms complications bacterial adherence biliary stent blockage biofilm bacteria hydrophilic polymer hydromercoated polyurethane stents endoscopic stenting

B, Jansen L P, Goodman D, Ruiten,.Bacterial adherence to hydrophilic polymer-coated polyurethane stents.. 39 (5),670-3.

B, Jansen L P, Goodman D, Ruiten,"Bacterial adherence to hydrophilic polymer-coated polyurethane stents." 39

B, Jansen L P, Goodman D, Ruiten,"Bacterial adherence to hydrophilic polymer-coated polyurethane stents."