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Acta oto-laryngologica | Vol.107, Issue.1-2 | | Pages 80-4

Acta oto-laryngologica

The effect of arginine-vasopressin and its analogues upon the endocochlear potential in the guinea pig.

N, Mori A, Shugyo H, Asai  
Abstract

The effect of arginine-vasopressin (AVP) and its analogues upon the endocochlear potential (EP) was examined in the guinea pig. AVP decreased the EP reversibly and dose-dependently like lysin-vasopressin (LVP). V1 antagonist failed to block the effect of AVP upon the EP. V2 agonist reversibly decreased the EP like AVP. The results suggest that V2 receptors mediate the action of vasopressin on the EP.

Original Text (This is the original text for your reference.)

The effect of arginine-vasopressin and its analogues upon the endocochlear potential in the guinea pig.

The effect of arginine-vasopressin (AVP) and its analogues upon the endocochlear potential (EP) was examined in the guinea pig. AVP decreased the EP reversibly and dose-dependently like lysin-vasopressin (LVP). V1 antagonist failed to block the effect of AVP upon the EP. V2 agonist reversibly decreased the EP like AVP. The results suggest that V2 receptors mediate the action of vasopressin on the EP.

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N, Mori A, Shugyo H, Asai,.The effect of arginine-vasopressin and its analogues upon the endocochlear potential in the guinea pig.. 107 (1-2),80-4.

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