The number of survivors of E. coli strains B/r or 15T- following X-ray exposure was increased if the log phase cells had been previously grown in the presence of chloramphenicol. By omission of thymine in the growth medium of E. coli strain 15T- the chloramphenicol effect failed to materialize. Under these conditions net DNA synthesis was prevented while RNA continued to be accumulated. Since protein synthesis was inhibited by chloramphenicol under all conditions employed it would appear that the “surplus” DNA was responsible for the enhanced survival of cells so treated.

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e coli surplus dna growth

Daniel Billen,.Alterations in the radiosensitivity of Escherichia coli through modification of cellular macromolecular components. 34 (1),110-116.

Daniel Billen,"Alterations in the radiosensitivity of Escherichia coli through modification of cellular macromolecular components" 34

Daniel Billen,"Alterations in the radiosensitivity of Escherichia coli through modification of cellular macromolecular components"