American journal of Alzheimer's disease and other dementias | Vol.24, Issue.6 | | Pages 461-8
Longitudinal verbal fluency in normal aging, preclinical, and prevalent Alzheimer's disease.
Few longitudinal studies evaluate differences in patterns of change of category compared to letter fluency across the spectrum of cognitive impairment.We compared change in category (animal and supermarket) and letter (F, A, S) fluency among 239 participants in 3 groups: remained cognitively normal throughout follow-up (n = 96), developed Alzheimer's Disease (AD; preclinical AD, n = 21), and with AD at initial testing (prevalent AD, n = 122).At baseline, prevalent and preclinical AD groups scored lower on animal than letter fluency. On all fluency measures, the prevalent AD declined faster than other groups (all P < .0001), and preclinical AD declined faster than unimpaired (all P Original Text (This is the original text for your reference.) Longitudinal verbal fluency in normal aging, preclinical, and prevalent Alzheimer's disease.
Few longitudinal studies evaluate differences in patterns of change of category compared to letter fluency across the spectrum of cognitive impairment.We compared change in category (animal and supermarket) and letter (F, A, S) fluency among 239 participants in 3 groups: remained cognitively normal throughout follow-up (n = 96), developed Alzheimer's Disease (AD; preclinical AD, n = 21), and with AD at initial testing (prevalent AD, n = 122).At baseline, prevalent and preclinical AD groups scored lower on animal than letter fluency. On all fluency measures, the prevalent AD declined faster than other groups (all P < .0001), and preclinical AD declined faster than unimpaired (all P +More
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