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Izvestiia Akademii nauk. Seriia biologicheskaia / Rossi?skaia akademiia nauk | Vol., Issue.6 | | Pages 713-20

Izvestiia Akademii nauk. Seriia biologicheskaia / Rossi?skaia akademiia nauk

[Optimality of enzymatic physiological systems].

K V, Tiurin M A, Khanin  
Abstract

An optimality criterion is proposed for physiological systems based on limited proteolysis. The proposed criterion is applied to the prourokinase-activated fibrinolytic system, for which the existence of optimal (according to this criterion) substrate concentrations is demonstrated. It is also shown that the optimal substrate concentrations depend on the values of kinetic constants.

Original Text (This is the original text for your reference.)

[Optimality of enzymatic physiological systems].

An optimality criterion is proposed for physiological systems based on limited proteolysis. The proposed criterion is applied to the prourokinase-activated fibrinolytic system, for which the existence of optimal (according to this criterion) substrate concentrations is demonstrated. It is also shown that the optimal substrate concentrations depend on the values of kinetic constants.

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K V, Tiurin M A, Khanin,.[Optimality of enzymatic physiological systems].. (6),713-20.

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