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Clinical and experimental rheumatology | Vol.28, Issue.5 Suppl 61 | | Pages S95-101

Clinical and experimental rheumatology

Side effects and management of side effects of methotrexate in rheumatoid arthritis.

K, Albrecht U, Müller-Ladner  
Abstract

Low-dose methotrexate (MTX) remains the first-line treatment option among the disease-modifying antirheumatic drugs in patients with rheumatoid arthritis. However, diverse side effects are the major reason for MTX withdrawal and change of treatment. The following article reviews the published data on general and organ-specific side effects and outlines the current recommendations addressing prevention and management of MTX-associated adverse effects.

Original Text (This is the original text for your reference.)

Side effects and management of side effects of methotrexate in rheumatoid arthritis.

Low-dose methotrexate (MTX) remains the first-line treatment option among the disease-modifying antirheumatic drugs in patients with rheumatoid arthritis. However, diverse side effects are the major reason for MTX withdrawal and change of treatment. The following article reviews the published data on general and organ-specific side effects and outlines the current recommendations addressing prevention and management of MTX-associated adverse effects.

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K, Albrecht U, Müller-Ladner,.Side effects and management of side effects of methotrexate in rheumatoid arthritis.. 28 (5 Suppl 61),S95-101.

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