COVID-19 vaccination is a safe way to help the immune system build protection against COVID-19. Getting vaccinated significantly reduces the risk of severe disease, hospitalization and death. As universal eligibility for covid19 vaccine expands across the nation and millions of Americans are getting ready to get a life-saving vaccine, we offer a guide on what to do before, during and after receiving a COVID-19 vaccine. The more people who get vaccinated, the sooner we can end the pandemic.